SALL4 peptide FFW
CAS No. ——
SALL4 peptide FFW ( RRKFAKFQWI;FFW peptide )
产品货号. M17053 CAS No. ——
SALL4 peptide FFW (RRKFAKFQWI, FFW peptide) is a potent therapeutic SALL4 peptide antagonist of SALL4-NURD.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SALL4 peptide FFW
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述SALL4 peptide FFW (RRKFAKFQWI, FFW peptide) is a potent therapeutic SALL4 peptide antagonist of SALL4-NURD.
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产品描述SALL4 peptide FFW (RRKFAKFQWI, FFW peptide) is a potent therapeutic SALL4 peptide antagonist of SALL4-NURD (nucleosome remodeling deacetylase) interaction with target affinity of 23 nM; reverses Transcription Repression by SALL4-RBBp4, disrupts the SALL4-NuRD complex resulted in unidirectional up-regulation of transcripts, turning SALL4 from a dual transcription repressor-activator mode to singular transcription activator mode; displays significant antitumor effects, inhibiting tumor growth by 85% in xenograft mouse models of HCC.
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同义词RRKFAKFQWI;FFW peptide
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量1378.70
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分子式C67H103N21O11
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Arg-Arg-Lys-Phe-Ala-Lys-Phe-Gln-Trp-Ile-NH2
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Liu BH, et al. Proc Natl Acad Sci U S A. 2018 Jul 5. pii: 201801253.
产品手册
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